Britta Will Selected Research

proto-oncogene protein Spi-1

12/2017	Pharmacological inhibition of the transcription factor PU.1 in leukemia.
10/2015	Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia.
8/2008	PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.

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Britta Will Research Topics

Disease

11	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022 - 09/2007
9	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 12/2019 - 10/2009
8	Neoplasms (Cancer) 01/2022 - 10/2015
8	Leukemia 01/2022 - 08/2008
5	Thrombocytopenia (Thrombopenia) 10/2020 - 10/2009
2	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2022 - 07/2012
2	Disease Progression 01/2017 - 01/2017
2	Polycythemia Vera 02/2013 - 04/2010
1	Purpura 01/2022
1	Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic) 01/2022
1	Hematologic Neoplasms (Hematological Malignancy) 12/2019
1	Aplastic Anemia (Anemia, Hypoplastic) 10/2019
1	Bone Marrow Failure Disorders 12/2018
1	Primary Myelofibrosis (Myelosclerosis) 01/2017
1	Myeloid Leukemia (Leukemia, Myelocytic) 11/2016
1	Thrombocytosis (Thrombocythemia) 02/2013
1	Myeloproliferative Disorders (Myeloproliferative Disorder) 01/2012
1	Polyps 12/2010
1	Chromosome Aberrations (Chromosome Abnormalities) 09/2007

Drug/Important Bio-Agent (IBA)

6	eltrombopag FDA Link 01/2022 - 10/2009
3	Thrombopoietin ReceptorsIBA 12/2018 - 10/2009
3	proto-oncogene protein Spi-1IBA 12/2017 - 08/2008
3	Transcription Factors (Transcription Factor)IBA 10/2015 - 09/2007
2	ChromatinIBA 01/2022 - 12/2018
2	IronIBA 12/2018 - 07/2012
2	Biological ProductsIBA 11/2018 - 11/2015
1	DNA (Cytosine-5-)-Methyltransferases (DNA (Cytosine 5) Methyltransferase)IBA 01/2022
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2022
1	LY-2157299IBA 12/2019
1	Phosphotransferases (Kinase)IBA 12/2019
1	Chelating AgentsIBA 12/2018
1	Nuclear Proteins (Protein, Nuclear)IBA 01/2017
1	CytosineIBA 01/2017
1	A-Form DNA (A-DNA)IBA 01/2017
1	CateninsIBA 01/2017
1	RNA (Ribonucleic Acid)IBA 11/2016
1	Protein Isoforms (Isoforms)IBA 11/2016
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 11/2015
1	Lenalidomide (CC 5013)FDA Link 12/2014
1	fms-Like Tyrosine Kinase 3IBA 08/2012
1	NF-E2 Transcription FactorIBA 01/2012
1	arginylphenylalaninamideIBA 12/2010
1	ABT-737IBA 04/2010
1	Pharmaceutical PreparationsIBA 04/2010
1	Janus Kinase InhibitorsIBA 04/2010

Therapy/Procedure

9	Therapeutics 01/2022 - 08/2012
1	Drug Therapy (Chemotherapy) 10/2019
1	Transplantation 12/2017